Poster for Splice (2010)

Movie R

Splice (2010)

Jun 3, 2010 · 1h 44m

5.9/10 TMDB user score
2,546 votes on TMDB

She's not human...not entirely.

Elsa and Clive, two rebellious young scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators — only to have that bond turn deadly.

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Top cast

  • Adrien Brody Adrien Brody Clive Nicoli
  • Sarah Polley Sarah Polley Elsa Kast
  • Delphine Chanéac Delphine Chanéac Dren
  • Brandon McGibbon Brandon McGibbon Gavin Nicoli
  • Simona Măicănescu Simona Măicănescu Joan Chorot
  • David Hewlett David Hewlett William Barlow
  • Abigail Chu Abigail Chu Child Dren
  • Doug Hicton Lab tech (uncredited)

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